Cancer is one of the leading causes of death worldwide. It accounts for nearly one in six of all deaths. The disease involves uncontrolled cell growth with the ability to spread and invade other tissues and organs around the body.
Aggressive conventional cancer treatments are known to suppress and weaken the immune system. Immunax is a natural substance that helps to restore innate immune defense systems and improve outcomes for immune-compromised cancer patients.
Cancer cells have clever mechanisms to evade the immune system. They are able to disable the immune response by inhibiting the natural production of VDBP-MAF – an immune-modulating protein that activates macrophages.
Activated macrophages play a crucial role in identifying and destroying abnormal cells, including cancer cells, through multiple mechanisms such as phagocytosis and the release of immune signaling molecules to recruit other cancer-killing immune cells.
Cancerous cells and tumors suppress innate VDBP-MAF production by secreting an enzyme called nagalase (α-N- acetylgalactosaminidase). Nagalase removes sugar molecules from Vitamin D Binding Protein (VDBP), which produces a dysfunctional precursor protein and prevents its conversion into the activated messenger protein Vitamin D Binding Protein Macrophage Activating Factor (VDBP-MAF).
Elevated nagalase has been detected in many cancer patients, but not in healthy individuals. Studies have shown that elevated nagalase levels are associated with insufficient VDBP-MAF levels and immunosuppression [3]. Without adequate levels of VDBP-MAF the immune system is unable to activate macrophages and mount a coordinated immune response. Tumors grow unchecked and disease progresses rapidly.
iMAP therapy with Immunax supplements VDBP-MAF, which has been proven to activate macrophages, enabling them to identify and kill cancer cells [8]. Research has demonstrated the potential therapeutic efficacy of supplemental VDBP-MAF in various types of cancer, including [3]:
When macrophages are activated by VDBP-MAF it produces a cascade effect in the immune system and signals other immune cells. Activated macrophages can kill cancer cells directly and indirectly by recruiting cytotoxic T-cells, B-cells, natural killer (NK) cells and dendritic cells (DCs).
Macrophages also play a key role in regulating the tumor microenvironment, tumor growth, vascularization, metastatic spread and tumor response to various therapies. Immunax can be combined with other therapies as part of an integrative cancer care program and has been shown to work synergistically.
iMAP therapy with Immunax inhibits angiogenesis (blood vessel formation), proliferation and metastasis, which can help to slow or prevent disease progression [8] [9]. It can even reverse certain cancer cell processes and turn cancer cells back into healthy cells [35].
Incorporating Immunax into an integrative cancer treatment program can help to improve patient outcomes. The early and complementary application of immunotherapy has been shown to help:
A significant improvement in patient quality of life has been reported after Immunax treatment. Research indicates that VDBP-MAF not only enhances immune function and targets cancer cells, but may also reduce treatment related side-effects such as chemotherapy-induced:
Many cancer patients succumb to infections due to a weakened immune system. iMAP therapy is proven to boost the immune system. It may help to mitigate toxic side-effects, prevent the occurrence of infections, and enhance patient quality of life.